ODINECET Journals catalogue

This catalogue gives access to the Union List of serials available at the ODINECET-Group aquatic libraries. Full records of serials published in the ECET-region, and holdings per library at the following institutions are already included:

 

  • Russian Federal Research Institute of Fishery and Oceanography/VNIRO (Russia)
  • Polar Research Institute of Marine Fisheries and Oceanography (Russia)
  • Research Institute of the Azov Sea Fisheries Problems (Russia)
  • AtlantNIRO (Russia)
  • K.A. Timiryazev Moscow Agricultural Academy (Russia)
  • Limnological Institute RAN (Russia)
  • Institute of Biology of the Southern Seas (Ukraine)
  • Marine Hydrophysical Institute (Ukraine)
  • Estonian Marine Institute of the University of Tartu (Estonia)


A priority goal is to optimize Interlibrary Lending Service within the Association through improvement of the access to detailed information on serials available at the aquatic libraries of Central and Eastern Europe. Requests for articles from this catalogue can be sent through the EURASLIC mailinglist. For this service, you have to be a member of EURASLIC, please consult these pages to learn how to become a member.

All interested aquatic libraries in the ECET-region are invited to add information about their serial holdings to the List. Go to the ODINECET-website and contact the group responsible on how to join this initiative.

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Marine sponges: potential sources of new antimicrobial drugs
Laport, M.S.; Muricy, G. (2009). Marine sponges: potential sources of new antimicrobial drugs. Current Pharmaceutical Biotechnology 10(1): 86-105. https://dx.doi.org/10.2174/138920109787048625
In: Current Pharmaceutical Biotechnology. Bentham Science Publ Ltd: Sharjah. ISSN 1389-2010; e-ISSN 1873-4316, more
Peer reviewed article  
Available in  Authors 
    Vlaams Instituut voor de Zee: Non-open access 300669 [ request ]
Keyword
Author keywords
    Antibacterial; antifungal; antimicrobial; antiprotozoal; antiviral; resistance; sponge-associated bacteria; sponges
Authors  Top 
  • Laport, M.S.
  • Muricy, G.
Abstract
    Sponges (phylum Porifera) are sessile marine filter feeders that have developed efficient defense mechanisms against foreign attackers such as viruses, bacteria, or eukaryotic organisms. Marine sponges are among the richest sources of pharmacologically-active chemicals from marine organisms. It is suggested that (at least) some of the bioactive secondary metabolites isolated from sponges are produced by functional enzyme clusters, which originated from the sponges and their associated microorganisms. More than 5,300 different products are known from sponges and their associated microorganisms, and more than 200 new metabolites from sponges are reported each year. As infectious microorganisms evolve and develop resistance to existing pharmaceuticals, the marine sponge provides novel leads against bacterial, viral, fungal and parasitic diseases. Many marine natural products have successfully advanced to the late stages of clinical trials, as for example ara-A (vidarabine), an anti-viral drug used against the herpes simplex encephalitis virus. This substance is in clinical use for many years. Moreover, a growing number of candidates have been selected as promising leads for extended preclinical assessment, including manzamine A (activity against malaria, tuberculosis, HIV, and others), lasonolides (antifungal activity) and psammaplin A (antibacterial activity). In this review we have surveyed the discoveries of products derived from marine sponges and associated bacteria that have shown in vivo efficacy or potent in vitro activity against infectious and parasitic diseases, including bacterial, viral, fungal and protozoan infections. Our objective was to highlight the susbtances that have the greatest potential to lead to clinically useful treatments.
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